So, let’s just look at the facts shall we?
On October 3, 1849, Edgar Allan Poe was wandering the streets of Baltimore delirious, he was later described as being "in great distress, and... in need of immediate assistance", according to the man who found him, Joseph W. Walker. Rushed by carriage to the Washington Medical College, he died alone that hospital on Sunday, October 7, 1849, at 5:00 in the morning. Odd enough that Poe was in Baltimore (he was headed for Philadelphia) but the author of the macabre was never coherent long enough to explain how he came to be in his dire condition or... why he was wearing clothes that were not his own? According to witnesses, Poe is said to have repeatedly called out the name "Reynolds" on the night before his death although it was not clear to whom he was referring. Newspapers at the time reported the author's death as "congestion of the brain" or "cerebral inflammation", common euphemisms for deaths from disreputable causes such as alcoholism. Though Poe was known to drink to excess he was not a hopeless alcoholic, it is unlikely that his drinking him brought him to a strange city in strange clothes where he would die for unknown reasons.
I have always thought, since I wrote a paper on Poe in high school, that there was foul play but since all medical records, including his death certificate, have been lost since that time and Poe’s death remains shrouded in mystery.